"I am worried about him. I'm worried about me too. I think you'll be hard pressed to meet someone who doesn't have any secrets."

Basically, everyone's a target, even if it'll tend to go for the juicer secrets first. In Mystic Falls, they were luckily that Hope was keeping her literal existence from everyone. A whole lifetime as a secret was too delicious to have it going after any other targets.

"It wiped out a whole colony in a few days back in the sixteen hundreds. You've heard of Roanoke, right?"